ISSN
2277 - 3282
e ISSN
2277 - 3290
Publisher
Journal of Science
SYNTHESIS, CHARACTERIZATION, AND ANTIBACTERIAL ACTIVITY OF NEW SCHIFF'S BASES WITH 1, 2, 4-TRIAZOLE MOIETY
Author / Afflication
Yusra H. Alaraji
Department of Chemistry, College of Science, Al-Nahrain University, Jadria, Baghdad, Iraq.
Jawad K. Shneine
Department of Chemistry, College of Science, Al-Nahrain University, Jadria, Baghdad, Iraq.
Ahmad Najaf Ahmed A. Ahmed
Department of Chemistry, College of Science, Al-Nahrain University, Jadria, Baghdad, Iraq.
Keywords
Antibacterial Activity ,
Abstract
New Schiff 's bases with triazole ring (8a and 8b) have been synthesized from 4-Amino-5-((4-amino-5-phenyl-4H- 1,2,4-Triazol-3-ylthio)methyl)-4H-1,2,4-Triazole-3-thiol (7), which is built by multiple consecutive cyclization reactions starting from benzoic acid hydrazide (1). Infrared spectroscopy and melting points were used to characterize the synthesized compounds. The biological activity of compounds (7) and (8a and 8b) were evaluated toward gram negative bacteria (Escherichia coli) and gram positive bacteria (staphylococcus aureus).
Volume / Issue / Year
5 , 5 , 2015
Starting Page No / Endling Page No
293 - 299