ISSN
2277 - 3282
e ISSN
2277 - 3290
Publisher
Journal of Science
ANTI ULCEROGENIC ACTIVITY OF MOMORDICA CYMBALARIA IN RATS
Author / Afflication
P. Poli Reddy
Associate Professor, Department of Pharmacology, Swami Ramananda Tirtha Institute of Pharmaceutical Sciences, Nalgonda, Telangana, India
J. Venkateshwar Rao
Principal & Professor, Talla Padmavathi college of Pharmacy, Urus, Kareemabad, Warangal, Telangana, India.
K.R.S Sambasiva Rao
Department of Biotechnology, Acharya Nagarjuna University, Nagarjuna Nagar, Guntur, Andhra Pradesh, India
Keywords
Anti ulcerogenic activity ,Momordica cymbalaria , Phytochemical screening ,Pylorus ligation ,
Abstract
In the present work we have planned to screen anti ulcerogenic activity from fruit of Momordica cymbalaria belonging to family Cucurbitaceae. The fruit powder was extracted successively in both alcohol and aqueous and were subjected for phytochemical screening for determination of various Phytochemical constituents. Studies for both alcoholic and aqueous extracts were conducted up to the dose level of 2 g/kg by following OECD up and down method of guidelines No.425.The anti ulcerogenic activity was evaluated in various animal models like Pylorus ligation, aspirin, stress induced ulcer models in rats.
Volume / Issue / Year
5 , 5 , 2015
Starting Page No / Endling Page No
329 - 338